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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKCQ
All Species:
38.48
Human Site:
S695
Identified Species:
56.44
UniProt:
Q04759
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q04759
NP_006248.1
706
81865
S695
Q
N
M
F
R
N
F
S
F
M
N
P
G
M
E
Chimpanzee
Pan troglodytes
XP_001147999
706
81847
S695
Q
N
M
F
R
N
F
S
F
M
N
P
G
M
E
Rhesus Macaque
Macaca mulatta
XP_001083320
1140
127261
S1128
Q
S
A
F
A
G
F
S
F
V
N
P
K
F
E
Dog
Lupus familis
XP_849292
706
81555
S695
Q
N
M
F
R
N
F
S
F
I
N
P
G
M
E
Cat
Felis silvestris
Mouse
Mus musculus
Q02111
707
81555
S695
Q
N
M
F
S
N
F
S
F
I
N
P
G
M
E
Rat
Rattus norvegicus
Q9WTQ0
707
81732
S695
Q
N
M
F
S
N
F
S
F
I
N
P
G
M
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509836
708
81415
S697
Q
N
M
F
S
N
F
S
F
V
N
P
K
M
E
Chicken
Gallus gallus
NP_001006133
699
80179
S687
Q
S
A
F
A
G
F
S
F
T
N
P
K
F
E
Frog
Xenopus laevis
Q7LZQ8
671
76506
S657
Q
S
E
F
E
G
F
S
Y
V
N
S
D
F
S
Zebra Danio
Brachydanio rerio
Q7SY24
670
76288
S657
Q
D
E
F
E
G
F
S
F
I
N
P
E
F
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
S621
Q
D
E
F
A
G
F
S
F
V
N
P
K
F
G
Honey Bee
Apis mellifera
XP_394743
624
71014
D608
E
Q
I
L
A
S
M
D
Q
G
V
F
R
G
F
Nematode Worm
Caenorhab. elegans
P34722
704
80280
A673
D
D
F
T
N
E
K
A
A
L
T
P
V
H
D
Sea Urchin
Strong. purpuratus
XP_787505
585
66691
G574
I
N
Q
R
Q
F
R
G
F
S
F
T
N
P
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
T1118
S
Y
F
E
Q
E
F
T
S
A
P
P
T
L
T
Red Bread Mold
Neurospora crassa
P87253
1142
127954
T1111
S
N
F
D
S
E
F
T
S
V
T
P
V
L
T
Conservation
Percent
Protein Identity:
100
99.7
33.6
96.7
N.A.
94.7
94
N.A.
86.1
63.3
33.9
34.1
N.A.
42.9
43.2
47.1
47.8
Protein Similarity:
100
99.7
45.1
98.3
N.A.
97.5
96.8
N.A.
92.9
77.1
48.2
49.2
N.A.
58.7
58.9
64.1
62
P-Site Identity:
100
100
53.3
93.3
N.A.
86.6
86.6
N.A.
80
53.3
33.3
46.6
N.A.
46.6
0
6.6
13.3
P-Site Similarity:
100
100
66.6
100
N.A.
93.3
93.3
N.A.
86.6
60
53.3
60
N.A.
60
20
33.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.2
26.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
39.3
40.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
13
0
25
0
0
7
7
7
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
19
0
7
0
0
0
7
0
0
0
0
7
0
7
% D
% Glu:
7
0
19
7
13
19
0
0
0
0
0
0
7
0
50
% E
% Phe:
0
0
19
69
0
7
82
0
69
0
7
7
0
32
7
% F
% Gly:
0
0
0
0
0
32
0
7
0
7
0
0
32
7
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% H
% Ile:
7
0
7
0
0
0
0
0
0
25
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
7
0
0
0
0
0
25
0
0
% K
% Leu:
0
0
0
7
0
0
0
0
0
7
0
0
0
13
0
% L
% Met:
0
0
38
0
0
0
7
0
0
13
0
0
0
38
0
% M
% Asn:
0
50
0
0
7
38
0
0
0
0
69
0
7
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
7
82
0
7
7
% P
% Gln:
69
7
7
0
13
0
0
0
7
0
0
0
0
0
0
% Q
% Arg:
0
0
0
7
19
0
7
0
0
0
0
0
7
0
0
% R
% Ser:
13
19
0
0
25
7
0
69
13
7
0
7
0
0
7
% S
% Thr:
0
0
0
7
0
0
0
13
0
7
13
7
7
0
19
% T
% Val:
0
0
0
0
0
0
0
0
0
32
7
0
13
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
0
0
0
0
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _